Navigating Hormonal Transitions and Low Testosterone

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March 7, 2024

Last Updated: Feb. 20, 2026

As men get older, their bodies naturally change, and hormones are part of that story. Just like women experience menopause, some men go through “andropause,” a gradual shift in testosterone that can affect energy, mood, and overall well-being.

Testosterone, the primary sex hormone in males, is known for causing physical changes during puberty. Many are not aware that it can also affect sex drive, mood, muscle mass, and bone density.

Testosterone levels tend to drop in all men as they age. In fact, according to research, about four out of 10 men over age 45 have low testosterone, or “low T.”*

Here’s what you, and the people who love you, should know about this common condition:

What causes low T?

Many things can contribute to low testosterone, such as:

  • Certain medicines 
  • Aging. It’s normal for testosterone to decrease as you age 
  • Injury to the testicles, or surgery or radiation treatment in the groin area 
  • Long-term medical conditions, such as high blood pressure, diabetes, kidney or liver disease, coronary artery disease, or obesity 
  • Problems related to the pituitary gland or hypothalamus 
  • Low testosterone can also be present at birth 

A blood test is usually done to find out if you have low testosterone. If your doctor thinks low testosterone could be related to another medical problem, other tests may be done.

Because testosterone naturally decreases with age, your doctor can help determine whether low testosterone may be contributing to the changes you’re feeling.

What are the symptoms of low T?

Symptoms may include decreased libido, erectile dysfunction, and low energy. Other symptoms may include depressed mood, loss of muscle mass and body hair, increased body fat, weakened bones, breast discomfort, and hot flashes.

Everyone experiences these changes differently, so if something feels “off,” it’s always worth having a conversation with your doctor.

Is low T preventable?

While you can’t fully prevent age-related hormonal shifts, healthy daily habits can support more stable testosterone levels. This includes things like a heart-healthy diet, exercise, not smoking, and blood pressure monitoring.

How is low T treated?

There are many available options for testosterone replacement, including topical gels and patches, injections, and long-acting testosterone supplements. Testosterone supplements may increase PSA (prostate-specific antigen) levels, which may cause additional prostate-related symptoms in men with an enlarged prostate. Testosterone replacement can also lower sperm count, so it should not be used when trying to conceive.

By talking openly with your doctor, you can work together to create a personalized treatment plan that supports hormonal balance and improves your quality of life.  

*Rehagen, T. (2024, May 21). Keep Testosterone in Balance. WebMD. When and how to balance low T.  


Thank you to our content partners at Sharp HealthCare and Healthwise.

Disclaimer: This blog provides general health information and is not a substitute for professional medical advice, diagnosis, or treatment. Talk to your health care provider about your individual needs.